Linus Pauling Institute

About the Linus Pauling Institute: The Linus Pauling Institute at OSU is a world leader in the study of micronutrients and their role in promoting optimum health or preventing and treating disease. Major areas of research include heart disease, cancer, aging and neurodegenerative disease.

Hops compounds help with metabolic syndrome while reducing microbiome diversity

CORVALLIS, Ore. – Compounds from hops may combat metabolic syndrome by changing the gut microbiome and altering the metabolism of acids produced in the liver, new research at Oregon State University suggests.

The findings, published in Molecular Nutrition and Food Research, are a key advance in understanding how xanthohumol, a compound that contributes to hops’ flavor, and its derivatives work. That is an important step toward improving the lives of the estimated 35% of U.S. adults who suffer from metabolic syndrome.

Liver, colon cancer cells thwarted by compounds derived from hops

CORVALLIS – The plant that adds flavor, color and bitterness to beer also produces a primary compound that thwarts cancer cells, and two important derivatives of the compound do as well, new research at Oregon State University shows.

Unlike the primary compound, xanthohumol, known as XN, the derivatives don’t metabolize into phytoestrogens. Phytoestrogens are plant-based chemicals similar to female sex hormones that help some types of tumors grow and can cause other health problems as well.

Nobel laureate to speak at conference hosted by OSU’s Linus Pauling Institute

CORVALLIS, Ore. – A Nobel laureate whose discoveries have advanced treatments for heart disease and impotence will deliver a keynote public address at Oregon State University this summer, part of the Linus Pauling Institute’s biennial conference on vitamins, minerals and natural products and their effects on human health.

Registration is open to hear the presentation by Louis Ignarro, who earned the Nobel Prize in Physiology or Medicine in 1998 and is best known for his work with nitric oxide.

Nanofiber-based wound dressings induce production of antimicrobial peptide

CORVALLIS, Ore. – Nanofiber-based wound dressings loaded with vitamin D spur the production of an antimicrobial peptide, a key step forward in the battle against surgical site infections, or SSIs.

The findings by Oregon State University researchers and other collaborators, published Wednesday in Nanomedicine, are important because SSIs are the most common healthcare-associated infection and result in widespread human suffering and economic loss.

Study shows vitamin E needed for proper nervous system development

CORVALLIS, Ore. – In research with key ramifications for women of childbearing age, findings by Oregon State University scientists show that embryos produced by vitamin E-deficient zebrafish have malformed brains and nervous systems.

“This is totally amazing – the brain is absolutely physically distorted by not having enough vitamin E,” said Maret Traber, a professor in the OSU College of Public Health and Human Sciences.

Multivitamin, mineral supplement linked to less-severe, shorter-lasting illness symptoms

CORVALLIS, Ore. – Older adults who took a daily multivitamin and mineral supplement with zinc and high amounts of vitamin C in a 12-week study experienced sickness for shorter periods and with less severe symptoms than counterparts in a control group receiving a placebo.

The findings by Oregon State University researchers were published in the journal Nutrients.